Founded in 1952 and known at the time as the Brownsville Society for Crippled Children, the Moody Clinic was created by a woman who had a son with Cerebral Palsy. She grew frustrated with the lack of treatment options available in the community. A group of professionals then got together and spearheaded a clinic to help children with special needs.

During the beginning, the clinic started as a rehabilitation facility for physical therapy. The majority of patients were those with Cerebral Palsy, polio and other neuromuscular disabilities. Not long after, staff realize extra services were required for children's overall success. Speech/language and Occupational therapy were then added to the program.

Moody Clinic is a 501 (c) 3 non profit organization and a United Way of Southern Cameron County partner agency.